Full-scale, quantitative PET combined with a robust, cryogen-free MRI
The new nanoScan® systems follow the footsteps of the first ever commercially available integrated preclinical PET/MRI system introduced by Mediso in 2011. The new nanoScan® PET/MRI systems are now equipped with both high end PET with simultaneous capability and state-of-the-art superconducting MRI subsystems.
The in-line PET subsystem features real dynamic scanning with the best count rate performance and highest resolution on the market, designed for quantitative imaging of mice, rats and even larger animals. When complemented with the PET insert the system covers every possible application in molecular imaging.
The MRI subsystems equipped with robust cryogen-free superconducting translational 3T and ultra-high field 7T magnets enable high end in vivo imaging applications.
Dual PET Configuration
Simultaneous or sequential? The dual PET configuration offers the best performance for all PET/MRI studies
Full-scale PET-ring on the front guarantees unlimited quantitative imaging regardless the amount of radioactivity, acquisition time or animal size.
SiPM-based PET insert ensures simultaneous PET/MRI studies without any interference between the PET and MRI readout.
In-line PET: highest-resolution, large diameter PET-subsystem with the widest dynamic range
High performance, market leading PET identical with the one used in the nanoScan® PET/CT
Finest lutetium oxyorthosilicate (LYSO) crystal needles in a large-diameter ring and statistical depth of interaction (DOI) compensation offer highest resolution and homogeneous image quality over the entire field of view
Bore size and transaxial field of view enabling scanning of larger rats or multiple mice in both PET and MRI
Best minimal detectable activity on the market: 60 Bq (1.6 nCi)
Inherently optimized for longitudinal studies e.g. long-term cell tracking
Fully quantitative at 60 MBq (1.6 mCi) and beyond
Optimal for imaging of isotopes with short half-life (11C, 13N, 15O etc.)
PET insert offering simultaneous multiparametric imaging
Due to the high level of integration the nanoScan® PET insert offers uncompromised image quality while giving access to a unique way of hybrid imaging by obtaining information from functional, metabolic and physiological processes in a simultaneous manner.
Simultaneous PET/MRI imaging of total body mouse or rat brain
Providing high resolution and homogeneous image quality over the entire field of view as a result of using the finest LYSO crystal needles and statistical depth of interaction compensation
Removable, allowing access to the full-bore of the MRI and also making benchtop measurements possible
Available as an upgrade for existing PET/MRI 3T, 7T and MRI 3T, 7T installations or as a standalone system
Perfect Integration of PET and MRI
Complete PET/MRI workflow
Innovative gantry design enables perfect animal positioning resulting in accurate co-registered images
Using the rotatable touchscreen it is possible to start dynamic PET or MRI measurements right from the scanner opening. The same touchscreen can be used for easy tuning and matching of Tx/Rx volume coils.
The software suite developed by Mediso covers the complete workflow from image acquisition, attenuation correction and reconstruction to image fusion and analysis, without the need of any third party software.
Ultra low attenuation Brain imaging coils
We designed our brain array coils with special care to achieve the lowest possible attenuation at 511KeV.
Using the 2ch phased array coil excellent contrast can be achieved in the brain region with uncompromised PET performance.
Robust cryogen-free magnet
The core of the nanoScan® MRI systems is the most robust cryogen-free superconducting magnet ever built for preclinical applications. Uniquely on the market it features a back mounted cryocooler to reduce conducted vibrations and make maintenance easier.
The magnet uses conduction cooling to reach superconducting temperatures therefore the magnet is 100% cryogen-free thus does not require quench pipes or any cryogen filling.
No Faraday cages are needed as the magnet is self-shielded. Due to its unique design the scanner is tightly sealed during operation allowing for ultra-low noise conditions.
Its base is a NbTi solenoid with multiple corresponding coils to maximize homogeneity and shielding thus reaching state-of-the-art homogeneity of ±0.1 ppm @ 50 mm DSV and negligible fringe field outside the cryostat.
Transport from loading dock and siting in a relatively small space is easily accomplished, as the magnet is very light (<250kg) with a small, sleek footprint.